LYMPH•LOGISCH · Understand your symptoms

Recognising erysipelas: take red, hot skin seriously.

Has your skin suddenly become hot, painful and more swollen? Erysipelas is a bacterial infection requiring prompt medical care. Understand how it develops, why lymphoedema increases risk and what supports a return to oedema treatment.

What is erysipelas?

Erysipelas is a bacterial infection affecting upper skin layers and superficial lymph vessels, often involving streptococci. Infection extending deeper into skin and soft tissue is termed cellulitis or phlegmon. English-language guidance often uses “cellulitis” more broadly. This means infection, not cosmetic cellulite. [1]

How do bacteria enter the skin?

Small breaks can provide an entry point, including cracks between toes with athlete’s foot, wounds or irritated skin. The opening is not always visible. Impaired lymph transport changes local fluid balance and immune defence, making people with lymphoedema more susceptible. Infection can in turn place further strain on lymph pathways. It does not imply poor personal cleanliness. Infection may affect a leg, arm, breast or another area. [1], [3]

What signs might you notice?

New warmth, pain, swelling and spreading redness are typical. Colour changes can be less apparent on darker skin. Fever, chills and flu-like illness may occur but can be absent. Seek same-day medical assessment if infection is suspected. Marked confusion or drowsiness, circulatory problems or rapid severe deterioration require immediate medical help. [2], [3]

What is treated medically?

Antibiotics treat the bacterial infection. Choice, duration and whether tablets or hospital treatment are needed depend on severity and individual circumstances. Tell the clinician about lymphoedema. Worsening symptoms or no improvement within about 48 hours require reassessment. Take antibiotics according to the prescribed plan. [2], [3]

What about drainage and compression?

Manual lymphatic drainage is not performed on the affected region during an acute infection. Resumption depends on recovery and medical assessment. [6] Compression is considered separately: do not force a painful or poorly fitting garment. With professional advice, suitable compression is restarted as early as is comfortable and medically appropriate. This does not always require waiting until antibiotics are finished. [3], [7]

How can recurrence be prevented?

Well-adapted oedema care and an intact skin barrier matter. Appropriate moisturising and treatment of athlete’s foot, cracks and wounds are useful parts of prevention. After the acute phase, compression and movement are adapted to the findings. With recurrent infections, the medical team may also consider preventive antibiotics. This is an individual prescribing decision. [3], [7]

Research in context

What do the studies show?

Can compression reduce recurrence?

A 2020 randomised trial in 84 people studied chronic leg oedema and recurrent skin infections. Recurrence occurred in 15% with compression plus education and 40% with education alone. This small, unblinded trial stopped early. It supports prevention in this population rather than compression alone as treatment for acute infection. [4]

What does newer research on the acute phase show?

A small 2025 randomised trial with 34 analysed participants introduced adjustable compression one day after antibiotics began. Symptoms improved without observed worsening of infection from compression. It suggests possible early use in selected, medically supervised patients, not self-bandaging suspected infection or replacing antibiotics. [5]

Erysipelas needs prompt medical treatment. Good oedema and skin care can subsequently help reduce the risk of further episodes.

Studies and clinical sources
  1. IQWiG: Wundrose und Phlegmone

    Evidence-based patient information on bacterial skin infection and its causes

  2. NHS: Cellulitis

    Patient guidance on symptoms, antibiotics and recovery

  3. British Lymphology Society / LSN (2025)

    Specialist consensus on skin infection in lymphoedema, compression and prevention

  4. Webb et al. (2020)

    Randomised unblinded trial of 84 people with chronic leg oedema and recurrent infection; stopped early for benefit

  5. Dräger et al. (2025)

    Small randomised trial with 34 analysed participants: adjustable compression one day after starting antibiotics for lower-leg cellulitis

  6. Cancer Research UK (2026): Manual lymphatic drainage

    Clinically checked patient guidance on drainage and situations requiring avoidance or medical review

  7. Macmillan Cancer Support: Lymphoedema care

    Patient guidance on infection, compression and returning to oedema care

Reviewed: 16 October 2026. A selection of relevant sources, not a systematic review. Information cannot establish a diagnosis or replace an individual assessment.

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